Researchers identified GSK3α as a key checkpoint controlling stem cell identity across multiple cell types. Inhibiting it ...

BACKGROUND: Preeclampsia affects approximately 1 in 10 pregnancies, leading to severe complications and long-term health ...

Cancer stem cells (CSCs), a critical subpopulation within tumors, drive cancer initiation, progression, metastasis, relapse, ...

Understanding how cells transform into specialized types during human development is a central challenge in biology. This complex process, known as cell differentiation, holds the key to understanding ...

For stem cells to differentiate into the appropriate cell-type, transcription factors (TFs) must be tailored to highly specific expression patterns of lineage-specific genes. Abnormalities in the ...

There is a high unmet need for accessible, affordable, and high-quality fertility care, as approximately 1 in 6 people are affected by infertility worldwide. While meiotic failure is a major cause of ...

Researchers found stem cells and early descendants share RNA profiles, but differ in active gene production. Independent ...

A review in the Chinese Journal of Natural Medicines examines how natural products can improve the in vivo fate of mesenchymal stem cells (MSCs), with potential benefits for cell homing, survival, ...

First-line IO-based combinations provide clinically meaningful survival in sRCC, with outcomes affected by sex, metastatic sites, and IMDC risk. This RWE may support a tailored therapeutic approach on ...